CORTICAL BONE MECHANICS TECHNOLOGY.

The CBMT Platform: Mechanical Bone Quality, Quantified Non-Invasively.

OsteoDx has developed Cortical Bone Mechanics Technology (CBMT™), a radiation-free, noninvasive dynamic three-point bending test measuring flexural rigidity and damping in humans to characterize bone mechanical properties, quality, and strength. [R1-R5]

ONE MEASUREMENT ENGINE

CBMT was developed to translate vibration-based mechanical testing into practical bone health research and clinical study settings. The platform applies a controlled mechanical input at the forearm, captures the resulting frequency response, and uses a biomechanical model to derive quantitative measures of cortical bone mechanics.[R1-R4]

OsteoDx CBMT closeup in action
  1. Platform
INSIGHTS INTO STRUCTURAL BONE MECHANICS

How CBMT™ Works

CBMT applies controlled, low-amplitude mechanical stimulation over the ulna and measures the resulting vibrational response. Force and acceleration data are analyzed as frequency response functions fitted to a mechanical model of the skin-bone system; outputs include bending stiffness, flexural rigidity, and damping-related measures. [R1, R2]

 

CBMT is designed to be:

  • Non-invasive

    Mechanical assessment through the skin, without needles, injections, or surgical procedures.[R1-R4]
  • Free of ionizing radiation

    Uses controlled mechanical stimulation and vibration sensing, not ionizing radiation.[R4]
  • Low-force

    Controlled mechanical input designed for patient comfort and reproducibility.[R1]

  • Designed for repeat assessment

    A quantitative platform intended to support follow-up measurement in research and clinical study settings.[R5]

  • Efficient

    Completed in <10 minutes.[R1-R4]

The result is an objective mechanical profile of cortical bone.[R1-R5]

OsteoDx CBMT™ Device

MECHANICAL BONE QUALITY

What CBMT™ Quantifies

 

bending stiffness icon

Flexural rigidity

Derives flexural rigidity from bending stiffness and ulna length, reflecting bending resistance of the tested bone segment. [R1, R3, R4]

bending stiffness icon

Bone damping

Estimates damping-related behavior during vibration, providing insight into dynamic mechanical response. Avoid claims that damping is clinically validated unless supported by separate evidence. [R1]
A FOCUS ON CORTICAL BONE MECHANICS

Why Cortical Bone Matters

 

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Adult skeletal bone
mass

Cortical bone makes up roughly 80% of adult skeletal bone mass and forms the dense outer structure of long bones. [R7]

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Central to long-bone mechanics

The cortical compartment is a major contributor to bending, torsional, and compressive resistance in long bones. [R7-R10]

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Important with
aging

Age-related cortical thinning and porosity can degrade mechanical integrity, particularly at appendicular sites. [R8-R10]

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Well suited to
CBMT

CBMT focuses on the mid-diaphyseal ulna, a cortical-dominant region anatomically suited for non-invasive bending assessment. [R1, R4, R6]

Get in Touch

brighter future for bone health starts with
smarter measurements.

Whether you run a clinical site, a longevity clinic, or a fund — let's talk about how OsteoDx™ fits into your roadmap.

Selected Peer-Reviewed Reference List

Clicking on ↩ should return you to the original source, as some citations use the same reference in multiple locations on this page.

R1. Bowman L et al. In vivo assessment of cortical bone fragility. Curr Osteoporos Rep. 2020;18(1):13-22.
R2. Bowman L et al. Improvements to mechanical response tissue analysis. MethodsX. 2019;6:2408-2419.
R3. Bowman L et al. A new noninvasive mechanical bending test accurately predicts ulna bending strength in cadaveric human arms. Bone. 2019;120:336-346.
R4. Warden SJ et al. Fracture discrimination capability of ulnar flexural rigidity measured via Cortical Bone Mechanics Technology: study protocol for The STRONGER Study. JBMR Plus. 2024;8(1):ziad002.
R5. Dick A et al. Cortical bone mechanics technology signal quality maintains robustness across a range of biometric profiles. JBMR Plus. 2025;9(9):ziaf116.
R6. Clark BC et al In vivo mechanical assessment of cortical bone rigidity enhances fracture discrimination beyond DXA in postmenopausal women. J Bone Miner Res. 2026.
R7. Clarke B. Normal bone anatomy and physiology. Clin J Am Soc Nephrol. 2008;3 Suppl 3:S131-S139.
R8. Bala Y et al. Role of cortical bone in bone fragility. Curr Opin Rheumatol. 2015;27(4):406-413.
R9. Ramchand SK et al. The influence of cortical porosity on the strength of bone during growth and advancing age. Curr Osteoporos Rep. 2018;16(5):561-572.
R10. Zabaze RMD et al. Intracortical remodelling and porosity in the distal radius and post-mortem femurs of women: a cross-sectional study. Lancet. 2010;375(9727):1729-1736.