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Cortical Bone Mechanics Technology · CBMT™

Smarter
Measurements.
Stronger Bones.

OsteoDx has developed Cortical Bone Mechanics Technology (CBMT™), a radiation-free, noninvasive dynamic three-point bending test measuring flexural rigidity and damping in humans to characterize bone mechanical properties, quality, and strength. [R1–R6]

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Science & Evidence
OsteoDx CBMT™ Device

0

Radiation

<10 min

Non-invasive
assessment

>$10M

NIH-supported
R&D

Cortical Bone Mechanics Technology

Mechanical bone quality, quantified non-invasively.

CBMT™ applies controlled, low-amplitude multi-frequency vibration over the ulna and analyzes the resulting frequency response to estimate bending stiffness, flexural rigidity, and damping-related parameters – measures that characterize how cortical bone behaves under bending-related loading. [R1–R5]

Science Behind CBMT

From gentle input to mechanical response.

CBMT applies a controlled mechanical input at the forearm and captures the ulna’s frequency response. The measurement is analyzed to generate objective metrics of cortical bone mechanics – designed to characterize fracture-relevant mechanical bone quality without ionizing radiation.[R1–R5]

  • Step 1

    Apply

    A controlled, low-amplitude vibration is applied over the ulna using gentle forces designed for non-invasive assessment.[R1]
  • Step 2

    Measure

    CBMT captures the vibrational response of the forearm and fits it to a mechanical model to estimate ulnar bending stiffness, flexural rigidity, and damping-related parameters.[R1–R4]
  • Step 3

    Report

    CBMT-derived metrics are organized into interpretable outputs for research, clinical-study, and future bone-health applications.

EVIDENCE

Built on clinical evidence and translational science.

CBMT™ has been evaluated in peer-reviewed multicenter clinical research and is supported by NIH-funded development, academic deployment, and peer-reviewed studies of cortical bone mechanics. [R4–R6]

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GET IN TOUCH

Bring cortical bone mechanics into your program.

Whether you are building a clinical bone-health service, developing a prevention-focused wellness program, or exploring strategic partnership, let’s discuss how OsteoDx and CBMT™ align with your goals.

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Selected Peer-Reviewed Reference List

Clicking on ↩ should return you to the original source, as some citations use the same reference in multiple locations on this page.

R1. Bowman L et al., In vivo assessment of cortical bone fragility. Curr Osteoporos Rep. 2020;18(1):13-22. ↩
R2. Bowman L et al., Improvements to mechanical response tissue analysis. MethodsX. 2019;6:2408-2419. ↩
R3. Bowman L et al., A new noninvasive mechanical bending test accurately predicts ulna bending strength in cadaveric human arms. Bone. 2019;120:336-346. ↩
R4. Warden SJ et al., Fracture discrimination capability of ulnar flexural rigidity measured via Cortical Bone Mechanics Technology: study protocol for The STRONGER Study. JBMR Plus. 2024;8(1):ziad002. ↩
R5. Dick A et al., Cortical bone mechanics technology signal quality maintains robustness across a range of biometric profiles. JBMR Plus. 2025;9(9):ziaf116. ↩
R6. Clark BC et al., In vivo mechanical assessment of cortical bone rigidity enhances fracture discrimination beyond DXA in postmenopausal women. J Bone Miner Res. 2026. ↩
R7. Clarke B. Normal bone anatomy and physiology. Clin J Am Soc Nephrol. 2008;3 Suppl 3:S131-S139. ↩
R8. Bala Y et al., Role of cortical bone in bone fragility. Curr Opin Rheumatol. 2015;27(4):406-413. ↩
R9. Ramchand S et al., The influence of cortical porosity on the strength of bone during growth and advancing age. Curr Osteoporos Rep. 2018;16(5):561-572. ↩
R10. Zabaze RMD et al., Intracortical remodeling and porosity in the distal radius and post-mortem femurs of women: a cross-sectional study. Lancet. 2010;375(9727):1729-1736. ↩